» Publications

SCI-SSCI or SCI Expanded Articles

H.NAZLI, B.MESUT, Ö.AKBAL-DAĞISTAN, Y.ÖZSOY " A Novel Semi-Solid Self-Emulsifying Formulation of Aprepitant for Oral Delivery: An In Vitro Evaluation" Pharmaceutics, 15(5), 1509, 2023 https://doi.org/10.3390/pharmaceutics15051509. (May 2023)

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G. GEDİK, C. K. OZTABAG, O. SARP, H. NAZLI, G. TIRANBESLİ, A. H. KURT, E. DINC, L. AYAZ "Development of Anti-VEGF Prolonged Release Drug Delivery System Containing PLL Dendrimer and Hyaluronic Acid" Russian Journal of Bioorganic Chemistry, 2022 DOI:https://doi.org/10.1134/S1068162022060115 (October 2022)

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H.NAZLI, B.MESUT, Y.ÖZSOY "In Vitro Evaluation of a Solid Supersaturated Self Nanoemulsifying Drug Delivery System (Super-SNEDDS) of Aprepitant for Enhanced Solubility" Pharmaceuticals 14 (11): 1089, 2021 DOI:https://doi.org/10.3390/ph14111089 (November 2021)

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Shanthi N, Mittal H, Kumar M, Mahato AK, Mishra B. Formulation, Optimization and Evaluation of Dabigartan Etexilate Encapsulated Solid Supersaturated Self-Nanoemulsifying Drug Delivery System. Current Nanomedicine (Formerly: Recent Patents on Nanomedicine). 2024 Jul 1;14(2):143-54. (July 2024)
Ganguly S, Sasi A, Nagaraju SK, Bakhshi S. Anti-Emetics in Children Receiving Chemotherapy for Solid Tumors and Leukemia: Pharmacology and Optimization of Therapy for Nausea and Vomiting. Pharmaceuticals. 2024 May 10;17(5):616. (May 2024)
J. S. KIM, F. U. DIN, H. J. CHO, Y. J. CHOI, M. R. WOO, S. CHEON, S. H. JI, S. PARK, Y. S. YOUN, K. T. OH, S. LIM, S. G. JIN, H. CHOI “Impact of carrier hydrophilicity on solid self nano-emulsifying drug delivery system and self nano-emulsifying granule system” International Journal of Pharmaceutics 648. https://doi.org/10.1016/j.ijpharm.2023.123578. (December 2023)
P. MOHITE, R. NANGARE, R. PANDHARE, A. PAWAR “Self-Nanoemulsifying Drug Delivery System of Loratidine for Improved Solubility: Physicochemical Characterization and In vitro Study” Letters in Applied NanoBioScience 13(1):30 https://doi.org/10.33263/LIANBS131.030. (August 2023)
J. MUDASSIR, A. RAZA, M. A. KHAN, H. HAMEED, G. A. SHAZLY, A. IRFAN, S. J. RANA, K. ABBAS, M. S. ARSHAD, S. MUHAMMAD, Y. A. BIN JARDAN “Design and Evaluation of Hydrophobic Ion Paired Insulin Loaded Self Micro-Emulsifying Drug Delivery System for Oral Delivery” Pharmaceutics, 15(7): 1973, https://doi.org/10.3390/pharmaceutics15071973. (July 2023)
Y. PİRİNCCİ TOK, B. MESUT, S. GUNGOR, A. O. SARIKAYA, E. E. ALDENIZ, U. DUDE, Y. ÖZSOY "Systematic Screening Study for the Selection of Proper Stabilizers to Produce Physically Stable Canagliflozin Nanosuspension by Wet Milling Method" Bioengineering 10(8): 927 https://doi.org/10.3390/bioengineering10080927. (July 2023)
H. NAZLI, B. MESUT, Ö. AKBAL-DAĞISTAN, Y. ÖZSOY "A Novel Semi-Solid Self-Emulsifying Formulation of Aprepitant for Oral Delivery: An In Vitro Evaluation" Pharmaceutics 15(5):1509. https://doi.org/10.3390/pharmaceutics15051509. (May 2023)
"Formulation Development, Optimization, and Characterization of Entrectinib-Loaded Supersaturable Self-Nanoemulsifying Drug Delivery Systems" BioNanoScience 2023 13:521–540. https://doi.org/10.1007/s12668-023-01094-1 (April 2023)
M. R. REDDY, K. S. GUBBIYAPPA "Formulation Development, Optimization, and Characterization of Entrectinib-Loaded Supersaturable Self-Nanoemulsifying Drug Delivery Systems" BioNanoScience 2023. https://doi.org/10.1007/s12668-023-01094-1 (April 2023)
T. Z. WANG, X. X. LIU, S. Y. WANG, Y. LIU, X. Y. PAN, J. J. WANG, K. H. NAN, "Engineering Advanced Drug Delivery Systems for Dry Eye: A Review" Bioengineering 10(1):53. https://doi.org/10.3390/bioengineering10010053 (December 2022)
M. R. REDDY, K. S. GUBBIYAPPA "Formulation development, optimization and characterization of Pemigatinib-loaded supersaturable self-nanoemulsifying drug delivery systems" Future Journal of Pharmaceutical Sciences 8 (45): https://doi.org/10.1186/s43094-022-00434-4 (November 2022)
M. REHMAN, M. Z. KHAN, S. GITE, M. TAYYAB, A. MADNI, Q. KHALID "Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs" Journal of Visualized Experiments 2022 (185) https://doi.org/10.3791/63995 (July 2022)
P. KAKADE, Z. PATHAN, S. GITE, A. MIRANI, V. B. PATRAVALE "Nanoparticle Engineering of Aprepitant Using Nano-by-Design (NbD) Approach" AAPS PharmSciTech 23:204, https://doi.org/10.1208/s12249-022-02350-5 (July 2022)
A. SHARMA, K. ARORA, H. MOHAPATRA, R. K. SINDHU, M. BULZAN, S. CAVALU, G. PANESHAR, H. O. ELANSARY, A. M. EL-SABROUT, E. A. MAHMOUD, A. ALAKLABI "Supersaturation-Based Drug Delivery Systems: Strategy for Bioavailability Enhancement of Poorly Water-Soluble Drugs" Molecules 27: 2969, https://doi.org/10.3390/molecules27092969. (May 2022)

H.NAZLI, G.GEDİK "In-vitro Evaluation of Dendrimeric Formulation of Oxaliplatin" Pharmaceutical Development and Technology 26 (7): 750-764, 2021 DOI:https://doi.org/10.1080/10837450.2021.1944205 (June 2021)

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Sonam S, Patel P, Jain K. PAMAM dendrimer and carbon quantum dots complexes as theranostic nanocarrier: Synthesis, optimization and photophysical characterization. Optics & Laser Technology. 2024 Aug 1;175:110761. (August 2024)
Santos, J.A.V.; Silva, D.; Marques, M.P.M.; Batista de Carvalho, L.A.E. Platinum-based chemotherapy: trends in organic nanodelivery systems. Nanoscale 2024, http://doi.org/10.1039/D4NR01483A. (July 2024)
Santos, J.A.V., Silva, D., Marques, M.P.M., Batista de Carvalho, L.A.E., 2024. Platinum-based chemotherapy: trends in organic nanodelivery systems. Nanoscale. htpps://doi.org/10.1039/D4NR01483A. (July 2024)
Mahaki H., Mansourian M., Meshkat Z., Avan A., Hossein S. M., Mahmoudian A. R., Ghorbani E., Ferns A. G., Manoochehri H., Menbari S., Sheykhhasan M., Tanzadehpanah H. "Nanoparticles Containing Oxaliplatin and the Treatment of Colorectal Cancer, Current Pharmaceutical Design" 2023; 29 (38). https://dx.doi.org/10.2174/0113816128274742231103063738 (November 2023)
Gautam D, Talwan P, Kumar S, Joshi G, Singh R. "Nanotechnological Carriers in the Treatment of Cancer: A Review" Current Nanomedicine 2023 13 (3) DOI: 10.2174/0124681873270774231008100554 (November 2023)
Kumari L, Choudhari Y, Patel P, Gupta GD, Singh D, Rosenholm JM, Bansal KK, Kurmi BD. Advancement in Solubilization Approaches: A Step towards Bioavailability Enhancement of Poorly Soluble Drugs. Life. 2023 May;13(5):1099. https://doi.org/10.3390/life13051099 (April 2023)
G. GEDİK "Formulation of an anti-aging cream containing Alteromonas ferment extract and evaluation of the effect on collagen concentration" 2023. Journal of Research in Pharmacy 27 (2): 903-912. Http://dx.doi.org/10.29228/jrp.370 (March 2023)
G. GEDİK, C. K. OZTABAG, O. SARP, H. NAZLI, G. TIRANBESLİ, A. H. KURT, E. DINC, L. AYAZ "Development of Anti-VEGF Prolonged Release Drug Delivery System Containing PLL Dendrimer and Hyaluronic Acid" Russian Journal of Bioorganic Chemistry, 2022 DOI:https://doi.org/10.1134/S1068162022060115 (October 2022)

International Articles

H.NAZLI, B.MESUT, Y.ÖZSOY "Pharmaceutical Approaches for Low Solubility Agents and Solubility of Aprepitant" FABAD Journal of Pharmaceutical Sciences 46 (3): 325-344, 2021. (December 2021)

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G.GEDİK, H.ASAN, A.ÖZYURT, A.ASAN, H.ALLI, H.NAZLI, Ö.SARP, "Effect of gel formulation obtained from Fomes fomentarius on bleeding and clotting time: A pilot study" İstanbul Journal of Pharmacy 50 (3): 216-223, 2020 (December 2020)

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F.C.KORUCU, H.NAZLI, G.GEDİK, İ.ÇİÇİN "Potential Problems of Biosimilars in Clinical Practice" Marmara Pharmaceutical Journal (Journal of Research in Pharmacy) 20: 44-51, 2016 (January 2016)

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International Conference Proceedings

M. ERDOĞMUŞ, H. NAZLI, A. S. SALAN, İ. YÜCE, N. BECENEN, G. GEDİK "Evaluation of the Effectiveness of Textile Materials Dyed with Rubia Tinctorum" Poster No:9 II. International Edirne Red Symposium "Natural Colorants from Plants" 2-5 October Edirne / Türkiye (October 2023)

H.NAZLI, B.MESUT, Y.ÖZSOY "Self Nanoemulsifying Drug Delivery System (SNEDDS) Formulation Design of Aprepitant" Oral Presentation No:OP-38 8th BBBB International Conference on Pharmaceutical Sciences 14-16 October İzmir / Türkiye (October 2019)

H.NAZLI, B.MESUT, Ş.H.TEKARSLAN ŞAHİN, Y.ÖZSOY "Self Nanoemulsifying Drug Delivery System (SNEDDS) Formulation Design of Aprepitant" Poster No:12 19th International Pharmaceutical Technology Symposium 17-19 September Antalya / Türkiye (September 2018)

International Conferences and Symposiums

II. International Edirne Red Symposium "Natural Colorants from Plants" 2-5 October Edirne / Türkiye - Symposium Secretary (October 2023)

19th International Pharmaceutical Technology Symposium 17-19 September Antalya / Türkiye (September 2018)
4th Pulmonary Drug Delivery Workshop 2017 19-21 September Istanbul / Turkey (September 2017)

National Conference Proceedings

G.GEDİK, Ö.SARP, H.NAZLI, Ç.OLTULU, Ö.GÜNDÜZ "New approaches to model neuropathic pain with oxaliplatin in mice" Poster No:31 1st National Marmara Pharmacy Congress 3-5 November İstanbul / Turkey (November 2016)

G.GEDİK, H.NAZLI "Dendrimeric oxaliplatin" Poster No:26 1st National Marmara Pharmacy Congress 3-5 November İstanbul / Turkey (November 2016)

F.C.KORUCU, H.NAZLI, Y.BAYEZIT, İ.ÇİÇİN "Pharmaceutical practices to avoid chemotherapy related errors" Poster No:108 5th Turkish Medical Oncology Convention 19th-23rd March Antalya / Turkey (March 2014)

National Conferences and Symposiums

TÜBİTAK 1000 Projects R&D Strategy Workshop (December 2016)
1st National Marmara Pharmacy Congress 3-5 November İstanbul / Turkey (November 2016)
Good Clinical Practice Training Meeting (September 2015)
Advanced Technology Products and Repayment (TUFTAD) (May 2015)

Referee Positions

International Journal Reviewer: Bionanoscience (May 2024)
International Journal Reviewer: Journal of Research in Pharmacy (September 2023)
International Journal Reviewer: Journal of Research in Pharmacy (February 2023)
International Journal Reviewer: Journal of Research in Pharmacy (January 2023)
International Journal Reviewer: Journal of Research in Pharmacy (December 2022)
International Journal Reviewer: Journal of Research in Pharmacy (November 2022)
International Journal Reviewer: Journal of Research in Pharmacy (September 2022)
International Journal Reviewer: Journal of Research in Pharmacy (August 2022)
International Journal Reviewer: Journal of Research in Pharmacy (June 2022)
International Journal Reviewer: Journal of Research in Pharmacy (June 2022)
International Journal Reviewer: Journal of Research in Pharmacy (June 2022)

Projects

Rapid clonal micropropagation in Rubia tinctorum L. (Madder plant), biotechnological production of "Edirne Red" dye and development of nanotechnological formulations. Trakya University Scientific Research Projects Unit - Research Project (Project Number:2024/148) Task: Researcher (July 2024)

Evaluation of the Antimicrobial Effects of Formulations Prepared Using Rubia tinctorum, which gives life to Edirne Red. Trakya University Scientific Research Projects Unit - Research Project (Project Number:2022/206) Task: Researcher (March 2024)

In Search of the Edirne Rose: To reveal the similarities between the genotypes of the oil rose (Rosa damascena Mill.) brought from Bulgaria and Isparta and the genotypes grown in Edirne in terms of phenolic compounds and to develop pharmaceutical solid dosage forms from these roses. Trakya University Scientific Research Projects Unit - Research Project (Project Number:2022/206) Task: Researcher (December 2023)

Obtaining extracts from coneflower species (Echinacea sp.) grown in Edirne and harvested at different growth periods, examining various properties of extracts and developing pharmaceutical dosage forms. Trakya University Scientific Research Projects Unit - Research Project (Project Number:2023/138) Task: Researcher (September 2023)

Production of Polyamidoamine dendrimers containing oxaliplatin, patent support project. Trakya University Scientific Research Projects Unit - Patent Support Project (Project Number:2023/75) Task: Researcher (May 2023)

Investigation of anti-microbial and anti-tumoral effects of selenium nanoparticles obtained from some edible mushrooms by green synthesis method on hepatocellular carcinoma (HCC) cells. Trakya University Scientific Research Projects Unit - Research Project (Project Number:2022/128) Task: Researcher (August 2022)

Self-Nanoemulsifying Solid Dosage Forms to Increase Solubility of BCS Class II Aprepitant. Trakya University Scientific Research Projects Unit - Property Rights and Patent Support Project (Project Number:2022/66) Task: Project coordinator (April 2022)

Polyamidoamine (PAMAM) dendrimers containing oxaliplatin for therapeutic purposes and their production method. Trakya University Scientific Research Projects Unit - European patent application project Task: Researcher (December 2021)

Polyamidoamine (PAMAM) dendrimers containing oxaliplatin for therapeutic purposes and their production method. Trakya University Scientific Research Projects Unit - Property Rights and Patent Support Project (Project Number: 2020/26) Task: Researcher (February 2020)

Development and in vitro, in vivo evaluation of novel self-emulsifying formulations of low solubility active substance. İstanbul University Scientific Research Projects Unit - Research Project (Project Number: 2019/29467) Task: Researcher (June 2019)

In-vitro evaluation of the dendrimeric formulation of oxaliplatin. Trakya University Scientific Research Projects Unit - Research Project (Project Number: 2016/165) Task: Researcher (July 2016)

Awards

Inventor Selected for Pharmaist 2022 Fair by Turkish Patent and Trademark Office (TURKPATENT) (May 2022)

Certificates

Horizon 2020 VIRT2UE Research Integrity Programme Certificate (January 2021)
PerkinElmer Spectrum TWO FT-IR Instrument Certificate (October 2020)

High Performance Liquid Chromatography (Agilent 1260 Infinity II series Prime HPLC) Training Certificate (September 2020)

Trakya University Ethics Board of Animal Experiments / Certificate of Experimental Animal Use (December 2013)

Other

Patent "Polyamidoamine (PAMAM) dendrimers containing oxaliplatin for therapeutic purposes and their production method" TR 2020/10694 (February 2022)

» Educational Qualifications

Bachelor`s Degree » Graduated in 2012

Bachelor`s Degree Thesis;

Master`s Degree » Graduated in 2019

Master`s Degree Thesis;

Doctoral Degree » Graduated in 2021

Doctoral Degree Thesis;

» Academic Titles

Research Assistant » In 2015

Research Assistant Doctor » In 2021

» Professional Experience

Trakya University Faculty of Pharmacy Department of Pharmaceutical Technology

Istanbul University Faculty of Pharmacy Department of Pharmaceutical Technology