» Educational Qualifications

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» Publications

SCI-SSCI or SCI Expanded Articles

  • Immunogenicity and protection efficacy of a COVID-19 DNA vaccine encoding spike protein with D614G mutation and optimization of large-scale DNA vaccine production (June 2024)
  • Yilmaz H ve Hamarat Sanlier S. "A novel second-generation platinum derivative and evaluation of its anti-cancer potential". Braz. J. Pharm. Sci. 2022; 58: e20954. https://doi.org/10.1590/s2175-97902022e20954 (January 2023)
  • Yilmaz Z. "A pH-Sensitive Chitosan/Oxidized-Kappa-Carrageenan based Nano-Antibiotic for Sustained and Controlled Release of Amoxicillin" Journal of Macromolecular Science, Part B: Physics, 2022, 62(7-8), 926-941. DOI: 10.1080/00222348.2022.2119328. (October 2022)
  • Yılmaz H., Ak G., Özmen G., Karasulu E., Hamarat Şanlıer Ş., "System Suitability Testing of the Method Developed to Measure the Active Concentration of a Fab Fragment Via Surface Plasmon Resonance" J. Mex. Chem. Soc., 2021, 65(4), 491-500, http://dx.doi.org/10.29356/jmcs.v65i4.1527. (October 2021)
  • An intravenous application of magnetic nanoparticles for osteomyelitis treatment: An efficient alternative (January 2021)
  • Hamarat Şanlıer Ş., Ak G., Yılmaz H., Ünal A., Bozkaya Ü.F., Tanıyan G., Yıldırım Y., Yıldız Türkyılmaz G., “Development of Ultrasound-Triggered and Magnetic-Targeted Nanobubble System for Dual-Drug Delivery”, Journal of Pharmaceutical Sciences, 108:3, 1272-1283, (2019).
  • Ak G., Yılmaz H., Güneş A., Şanlıer Ş., “In vitro and In vivo Evaluation of Folate Receptor Targeted a Novel Magnetic Drug Delivery System for Ovarian Cancer Therapy”, Artificial Cells, Nanomedicine and Biotechnology, 46:S1, 926-937, (2018). (February 2018)
  • Selvi Gunel N., Ozel B., Kipcak S., Aktan C., Akgun C., Ak G., Yilmaz H., Biray Avci C., Dodurga Y., Hamarat Sanlier S., “Synthesis of Methotrexate Loaded Chitosan nanoparticles and in vitro evaluation of the potential in treatment of prostate cancer”, Anti-Cancer Agents In Medicinal Chemistry, 16:8, 1038-1042 (5), 2016.
  • Hamarat Sanlier S., Yasa M., Cihnioglu A.O., Abdulhayoglu M., Yılmaz H., Ak G., “Development of gemcitabine adsorbed magnetic gelatin nanoparticles for targeted drug delivery to lung cancer”, Artificial Cells, Nanomedicine and Biotechnology, 44:(3), 943-949, (2015). (June 2015)
  • Akgul Y., Pazar E., Yilmaz H., Yurt Lambrecht F., Yılmaz O., Hamarat Sanlıer S., “Extraction, radiolabeling and in vivo biological evaluation of 131I labeled egonol glycosides extract”, Radiochimica Acta, 103:6, 457-462, (2015).
  • Yıldırım Y., Yılmaz H., Ak G., Hamarat Sanlier S., “New Copolymer of Acrylamide with Allyl Methacrylate and its Capacity for the Removal of Azo Dyes”, Revista Polímeros - Ciência e Tecnologia, 25:2, 137-145, (2015).
  • Zeybek A., Şanlı-Mohamed G., Ak G., Yılmaz H., Hamarat Sanlier S.,”In vitro evaluation of doxorubicin incorporated magnetic albumin nanospheres”, Chemical Biology and Drug Design, 84:1, 108-115, (2014). (June 2014)
  • Ak G., Yilmaz H., Hamarat Sanlier S., “Preparation of magnetically responsive albumin nanospheres and in vitro drug release studies” Artificial Cells, Nanomedicine and Biotechnology, 84:1, 108-115, (2014).
  • Yilmaz H., Hamarat Sanlier S., “Preparation of magnetic gelatin nanoparticles and investigating the possible use as chemotherapeutıc agent”, Artificial Cells, Nanomedicine and Biotechnology, 41:2, 69-77, (2013). (April 2013)
  • Hamarat Sanlier S., Ak G., Yılmaz H., Ozbakir G., Cagliyan O., “Removal of textile dye, Direct red 23, with glutaraldehyde cross-linked magnetic chitosan beads”, Prep Biochem Biotech, 43:2, 163-176, (2013). (January 2013)

International Conference Proceedings

  • Ayça Erek, Alparslan Semih Salan, Habibe Yılmaz, "Green Synthesis of Cerium Oxide Nanoparticles Using Turkish Coffee Waste Extract and Antimicrobial Evaluation", International Sustainability in Life Congress (SUIC), Oral presentation, 19-22 May, 2024, Aydın. (May 2024)
  • Yaren Güniz Uluçam, Habibe Yılmaz, Ufuk Usta, Selma Süer Gökmen, "Liposomal piperine as a nutrient based antioxidant regard to create sustainable medical formulations", International Sustainability in Life Congress (SUIC), Oral presentation, 19-22 May 2024. (May 2024)
  • Eray Çetin, Damla Baytok, Ferhunde Ceren Sevim, Ayça Erek, Habibe Yılmaz, "Investigation the Effects of Combi CLEAs Prepared with Bromelain and Cucumicin on Blood Clotting", International Sustainability in Life Congress (SUIC), Poster Presentation, 19-22 May 2024. (May 2024)
  • Ferhunde Ceren Sevim, Eray Çetin, Damla Baytok, Ayça Erek, Habibe Yılmaz, "Green Synthesis of Glutamine-Coated and Methotrexate Conjugated Zinc Oxide Nanoparticles", International Sustainability in Life Congress (SUIC), Poster Presentation, 19-22 May 2024. (May 2024)
  • Damla Baytok, Ferhunde Ceren Sevim, Eray Çetin, Ayça Erek, Habibe Yılmaz, "Dual-Drug Loaded Liposomal Nanoantibiotic System", International Sustainability in Life Congress (SUIC), Poster Presentation, 19-22 May 2024. (May 2024)
  • Habibe YILMAZ "Doxorubicin and Zinc Oxide Encapsulated Albumin Nanoparticles Exhibits pH-Sensitive Drug Release Profile", 2nd International Congress on Biological and Health Congress, Oral Presentation, Online, 24-27 February 2022. (February 2022)
  • Habibe Yılmaz, "Green Synthesized Silver Nanoparticles with Cotinus Coggygria Extract and Kappa-Carrageenan Has Antioxidant Capacity" The 5th International Conference on Materials Engineering and Nanotechnology, Oral Presentation, Virtual, 04-05.12.2021. (December 2021)
  • Yılmaz H, Hamarat Şanlıer Ş., "Synthesis and Characterization of a Novel Second Generation Platinum Derivative and Its Molecular Interaction Analysis via Surface Plasmon Resonance", 4th International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2021), Oral Presentation, 24-26 November 2021. (November 2021)
  • Döşkaya M., Gül A., Erkunt Alak S., Can H., Karakavuk M., Köseoğlu A.E., Karakavuk T., Gül C., Ün C., Gürüz A.Y., Yılmaz H., Karasulu E., Tekin Ş., Değirmenci Döşkaya A. "Administration of Four Different COVID-19 pcDNA 3.1 Vaccine Prototypes Using Intradermal Electroporation and Assement of Their Immunogenicity in Balb/c Mouse"2021 ISV Annual Virtual Congress, Poster presentation, Virtual Event, 13-15 September 2021. (September 2021)
  • Habibe YILMAZ, "SURFACE PLAZMON RESONANCE ANALYSIS OF A POTENTIAL INHIBITOR OF HISTONE DEACETYLASE 6 (HDAC6)" 2nd Global Virtual Conference on Pharmaceutical Sciences and Drug Development, Oral Presentation, Online Conference, 09-10 August 2021. (August 2021)

International Books and Book Chapters

  • Recent Progress in Pharmaceutical Nanobiotechnology: A Medical Perspective, Bölüm adı:(BIOINSPIRED, BIOMIMETIC NANOMEDICINES) (2023)., ŞANLIER ŞENAY, EREK AYÇA, YILMAZ HABİBE, Bentham Science Publishers, Editör:YILMAZ Habibe, Basım sayısı:1, Sayfa Sayısı 442, ISBN:978-981-5179-43-9, İngilizce(Bilimsel Kitap) (December 2022)
  • Recent Progress in Pharmaceutical Nanobiotechnology: A Medical Perspective, Bölüm adı:(ROLE OF NANO AND BIOPHARMACEUTICS IN PRECISION MEDICINE) (2023)., YILMAZ HABİBE, EREK AYÇA, Bentham Science Publishers, Editör:YILMAZ Habibe, Basım sayısı:1, Sayfa Sayısı 442, ISBN:978-981-5179-43-9, İngilizce(Bilimsel Kitap) (December 2022)
  • Theory and Research in Health Sciences II, Volume I, Editor: Prof. Dr. Cem Evereklioğlu, "Chapter 18 - Effective Factors in The Clinical Assesment and Bioanalysis of Biotherapeutics", Gece Kitaplığı, Ankara/Türkiye, ISBN: 978-625-7319-07-2. (December 2020)

National Articles

  • YILMAZ HABİBE (2022). Preparation and Characterization of Chitosan/κ-Carrageenan Based Polymeric Nanoparticles for Gemcitabine Delivery. Erzincan University Journal of Science and Technology, 15(2), 636-648. (August 2022)
  • Merve GÜREŞCİ, Güliz AK, Habibe YILMAZ, Şenay HAMARAT ŞANLIER, Armağan KINAL. "Computational Study on Pazopanib and Pemetrexed Anticancer Drug Molecules Interacting with a Small Peptide Link", Bulletin of Biotechnology, 2(1), 6-9, 2021. (May 2021)
  • Güliz Ak, Habibe Yılmaz, Şenay Şanlıer, “Laccase Isolation From Spent Mushroom Waste (Agaricus Bisporus): Partial Purification, Characterization, Immobilization And Biotechnological Application”, Eskişehir Teknik Üniversitesi Bilim Ve Teknoloji Dergisi C- Yaşam Bilimleri Ve Biyoteknoloji, 2021, 10(1), 43-55, DOI: 10.18036/Estubtdc.726398 (January 2021)
  • Yılmaz H., Ak G., Hamarat Şanlıer Ş., “Removal Of Hazardous Food Dye Brilliant Blue FCF From Aqueous Solution By Magnetic Crosslinked Chitosan Beads”, Hacettepe Journal of Biology and Chemistry, 40:1, 111-117, (2012).

National Conferences and Symposiums

  • In vitro / in vivo / ex vivo studies of the synthesis, characterization and cancer treatment potential of organometallic compounds for the inhibition of Hedgehog pathway in cancer treatment, Ege University Department of Biochemistry, Habibe Yılmaz, 22.04.2016.
  • Izmir Biomedicine and Genome Center Official Opening Event, D.E.U. Izmir Biomedicine and Genome Center, Izmir, 9-10.09.2015.
  • Cancer and Nanoparticular Systems Seminar, Ege University Department of Biochemistry, Habibe Yılmaz, 20.03.2015.
  • Seminar on the Preparation of Magnetic Gelatin Nanoparticles and Investigation of Their Use as Chemotherapy Agents, Ege University Department of Biochemistry, Habibe Yılmaz, 09.12.2011.
  • Stem Cell Symposium, Ege University, Ebiltem, 16.03.2009.
  • Nanobiotechnological Approaches Symposium, Ege University, Ebiltem, 07.03.2008.
  • Cancer Biochemistry Symposium, Ege University, Ebiltem, 02.03.2007.

Editorial Positions

  • Editor: Habibe Yilmaz, "Recent Progress in Pharmaceutical Nanobiotechnology: A Medical Perspective", Volume 8, ISBN: 978-981-5179-43-9, Bentham Science Publishers Pte. Ltd. Singapore. (December 2023)

Referee Positions

  • International Journal of Biological Macromolecules, Lactobionic Acid-modified Thymine-chitosan Nanoparticles as Efficient Carriers for Methotrexate Delivery (October 2020)
  • International Journal of Biological Macromolecules, Investigation of Anticancer Activity of an Antibacterial Drug, Rifampicin, on Human Breast Cancer Cells Through the Targeted Drug Delivery System Based Magnetic Molecular Imprinting Technology (October 2020)
  • International Journal of Nanomedicine, Cancer Cell Membrane Biomimetic Boron Nitride Nanospheres for Targeted Cancer Therapy (July 2020)
  • International Journal of Biological Macromolecules, “Hyaluronate-functionalized hydroxyapatite nanoparticles of Teriflunomide and Methotrexate for targeted delivery to avoid drug-induced hepatotoxicity in rheumatoid arthritis: In vivo imaging, Pharmacokinetic and Pharmacodynamic evaluation”, 14.09.2019.
  • International Research Journal of Medicine and Medical Sciences (IRJMMS), “Cytotoxicity Analysis of Etoposide and Cisplatin on Cell lines from Human Lungs cancer and Normal human lungs”, 05.04.2019.
  • Preparative Biochemistry & Biotechnology, “Hydrophilic and hydrophobic subproteome fractionation by use of TRIzol extraction and sequential chemical solubilization for 2DE-based proteomics from recalcitrant root tips of the medicinal plant, Hyoscyamus albus”, 25.03.2018.
  • Preparative Biochemistry & Biotechnology, “Proteomics investigation of molecular mechanisms affected by EnBase culture system in Anti-VEGF fab fragment producing E. coli BL21 (DE3)”, 18.06.2018.
  • Preparative Biochemistry & Biotechnology, “Medium pH in submerged cultivation modulates differences in the intracellular protein profile of Fusarium oxysporum URM 7401”, 26.12.2016.
  • Journal of Drug Targeting, “Evaluation of cancer imaging potential and photodynamic therapy efficacy of copper (II) benzyloxypheophorbide-a”, 19.07.2014 - 21.08.2014.
  • Journal of Drug Targeting, “Trapping effect on a small molecular drug with vascular disrupting agent CA4P in rodent H22 hepatic tumor model: in vivo magnetic resonance imaging and postmortem inductively coupled plasma atomic emission spectroscopy”, 01.12.2014.

Projects

  • “Development and Production of Monoclonal Antibody Active Substance Biosimilar Drug for Cancer and Osteoporosis Treatment”, Researcher / Specialist, TÜBİTAK 1007, Project Number: 115G017, 2017-2018.
  • In vitro / in vivo / ex vivo studies of the synthesis, characterization and cancer treatment potential of organometallic compounds for the inhibition of Hedgehog pathway in cancer treatment”, Researcher, Project Code: 16 FEN 007, 2016-2017.
  • Development of Magnetic and Ultrasound Targeted Drug Delivery System for IV Injection and / or Inhaler Application in Lung Cancer and In vitro / In vivo / Ex vivo Studies”, TUBITAK 1003, Project Code: 213M672, Scholar, 2017.
  • Investigation of Personalized Anti-Cancer Treatment Potential with Folate Receptor Targeted and Biomimetic Designed Magnetic Drug Delivery Systems
  • Nano-Sized Antibiotherapy for Osteomyelitis, Researcher, 2014 İLAM 001 BAP, 2017.
  • Investigation of Personalized Anti-Cancer Treatment Potential with Folate Receptor Targeted and Biomimetic Designed Magnetic Drug Delivery Systems
  • Synthesis of pemetrexed loaded magnetic O-carboxymethyl chitosan nanoparticles and investigation of their efficacy in lung cancer cell lines
  • Preparation of magnetic gelatin nanoparticles and investigation of their usage as a chemotherapy agent
  • “Biosimilar Products Research Center of Excellence”, Undersecretariat of State Planning Organization (DPT), Project Number 2010K120830 (10-DPT-001), Researcher / Expert, 2018-2020.

Awards

  • Damla Baytok, Ferhunde Ceren Sevim, Eray Çetin, Ayça Erek, Habibe Yılmaz, "Dual-Drug Loaded Liposomal Nanoantibiotic System", International Sustainability in Life Congress (SUIC), Poster Presentation, The best poster award. (May 2024)
  • Best oral presentation award with oral presentation titled “Measurement The Active Content of A Fab Fragment Containing Finished Product Via Surface Plasmon Resonance” at the 8th BBBB International Conference on Pharmaceutical Sciences Conference, İzmir, 14-16 October 2019. (October 2019)
  • Second prize in the product category with the poster titled "Development of the IV and Ultrases Targeted Drug Delivery System for Injection and / or Inhaler Application for Lung Cancer and In Vitro / In vivo / Ex vivo Studies" in the Life Sciences and Health Project Contest, Dokuz Eylül University Izmir Biomedicine and Genome Center, 9-10 September 2015. (September 2015)
  • Best poster award with the poster titled “Synthesis of dual drug and peptide decorated magnetic nanoparticles to address lung cancer” at the European Pharma Congress Congress, Spain, 25-27 August 2015. (August 2015)
  • Best poster award for the poster titled “Development of Nanoparticulate System for Ovarian Cancer Therapy” at the European Pharma Congress Congress, Spain, 25-27 August 2015. (August 2015)
  • Third prize in the 2nd Pharmaceuticals Chemistry, Production, Technology and Standardization Congress with the poster titled “Studies on the Imaging of Magnetic Nanoparticles Containing Texas Red Marked Cisplatin with IVIS Spect in Rats”, Antalya, 21-23 March 2014. (March 2014)
  • 18. E.O.G. Best hypothesis prize in “The Best Hypothesis” contest at The International Symposium on Cancer Nanomedicine congress, 7-9 November 2013. (November 2013)

Certificates

  • Good Clinical Practices Training, SBÜ Tepecik Training and Research Hospital, İzmir, 20.12-21.12.2018. (December 2018)
  • BD Flow Cytometer Workshop, BD, E.Ü. Bioengineering Department, Izmir, 13.11.2018. (November 2018)
  • Shimadzu UV-1800 Device User Training, Ant Teknik, Izmir, 25 December 2017. (December 2017)
  • Therapeutic mAb Engineering and Production Workshop, Izmir Biomedicine and Genome Center, Izmir, November 11, 2017. (November 2017)
  • PA800 Plus Pharmaceutical Analysis System Device User Training, AKA Biotechnology, Izmir, 09.10.2017. (October 2017)
  • Biacore™ Basics, Assay Development and Kinetic Evaluation Course, GE Healthcare Life Sciences, Izmir, 28.09.2017. (September 2017)
  • Waters Acquity H-Class Bio UPLC Systems and Empower 3 CDS Software Basic User Training, LiKrom Analytical Solutions Marketing Industry, and Trade Inc., Izmir, 27-28 July 2017. (July 2017)
  • Experimental Animal User Training Certificate Course, Istanbul University DETAE, Istanbul, 07-18 December 2015. (December 2015)
  • 7. Traditional Science and Technology Symposium: Personalized Medicine Treatment Symposium, EBİLTET, İzmir, 28.03.2015. (March 2015)
  • ProteOn XPR36 System Training, Ege University Research and Application Center of Drug Development and Pharmocokinetics (ARGEFAR), BioRad, İzmir, 18-19 November 2014. (November 2014)
  • Turkish-German Workshop on Bioinformatics: Recent Developments from Health to Nanotechnology, Kuşadası-Aydın, 19-22 Ekim 2014. (October 2014)
  • V3WW (Mini Protean Tetra Cell, Trans Blot Turbo, Chemi Doc MP Imaging System with LEDs), PDQuest Advanced Analysis Software, i12 IEF System, Ege University Research and Application Center of Drug Development and Pharmocokinetics (ARGEFAR), BioRad, Izmir, 18-19 August 2014 . (August 2014)
  • Effective Project Writing Training for Tübitak Project Calls, Ege University Science and Technology Center Technology Transfer Office, 20-22 November 2013. (November 2013)
  • Nano-medicine Applications Course in Oncology, Ege University, Faculty of Medicine, İzmir, 07.11.2013. (November 2013)
  • Pedagogical Formation Certificate Training, Ege University Faculty of Education, 7 February - 3 July 2013. (July 2013)
  • Electrophoresis, Spectrometry and Spectroscopy Based Proteomic Analysis Course, Ankara University, Ankara, June 17-18, 2013. (June 2013)
  • UHPLC (Introduction to Chromatography, HPLC, Columns and Application Techniques) and GCMS (Latest Technologies and Application Areas) Seminar, Ege University, 27.04.2012. (April 2012)
  • Cancer Biology Current Issues Course, Dokuz Eylul University, 31.05 - 03.06.2011. (June 2011)
  • ISO 22000: 2005 Food Safety Management System Certified Training, Ege University, Egasan, 07.03 - 08.03.2009. (March 2009)